abstract：:In a sample comprising 51 normotensive subjects and 51 subjects with in-clinic arterial hypertension [blood pressures (BPs) > or = 140/90 mmHg), we investigated the prevalence of target organ damage [left ventricular hypertrophy (LVH) and retinal vasculopathy] in white coat hypertension (WCH) groups defined using: (a)...

journal_title：Blood pressure

authors： Pose-Reino A,Rodríguez-Fernández M,López-Barreiro L,Coleman IC,Estévez-Nuñez JC,Méndez-Naya I

更新日期：2002-01-01 00:00:00

abstract：:Whole-body insulin sensitivity has been shown to be impaired in subjects with increased left ventricular relative wall thickness (RWT) and in hypertensive subjects with left ventricular hypertrophy, but the relation between myocardial insulin sensitivity and RWT or left ventricular mass index (LVMI) in normotension is...

journal_title：Blood pressure

authors： Sundström J,Lind L,Valind S,Holmäng A,Björntorp P,Andrén B,Waldenström A,Lithell H

更新日期：2001-01-01 00:00:00

abstract：:We compared the effects of amlodipine and verapamil slow release on autonomic responses to a 5-min mental arithmetic test (MST) in patients with mild to moderate hypertension. Twenty subjects received 8 weeks of verapamil slow release 240 mg or amlodipine 10 mg in a double-blind crossover design, both after 4 weeks' p...

journal_title：Blood pressure

authors： Sevre K,Lefrandt JD,Eide I,Smit AJ,Rostrup M

更新日期：2001-01-01 00:00:00

abstract：:In a previous study we investigated the differential time courses of the vasodilator effect of various calcium antagonists (CA) in small isolated rat mesenteric arteries (van der Lee et al., Fundam Clin Pharmacol, 1998: 12: 607-12). We concluded that the differences observed could be due to differences in lipophilicit...

journal_title：Blood pressure

authors： van der Lee R,Pfaffendorf M,Koopmans RP,van Lieshout JJ,van Montfrans GA,van Zwieten PA

更新日期：2001-01-01 00:00:00

abstract：:The reduction in blood pressure seen with the use of beta-blocking drugs was an unexpected finding. Initially there was resistance to their use as the reduction of cardiac output and increase in peripheral resistance from beta-blockade was considered an undesirable pharmacological action for a drug in the treatment of...

journal_title：Blood pressure

authors： Prichard BN,Cruickshank JM,Graham BR

更新日期：2001-01-01 00:00:00

abstract：OBJECTIVE:The aim of the present study was to determine if there is an association of different gene polymorphisms of renin-angiotensin system and left ventricular hypertrophy (LVH) in patients with essential hypertension (EH) in St Petersburg population. PATIENTS AND METHODS:We examined 156 patients (the mean age 49+...

journal_title：Blood pressure

authors： Shlyakhto EV,Shwartz EI,Nefedova YB,Zukova AV,Vinnic TA,Conrady AO

更新日期：2001-01-01 00:00:00

abstract：:Neurohormonal changes in congestive heart failure (CHF) include an enhanced peripheral sympathetic nerve activity which results in increased release of noradrenaline, neuropeptide Y and ATP. To examine if such changes in CHF would modulate peripheral pre- and postsynaptic receptors of ATP and its degradation product a...

journal_title：Blood pressure

authors： Zhao XH,Sun XY,Erlinge D,Edvinsson L,Hedner T

更新日期：2000-01-01 00:00:00

abstract：:Arterial hypertension is accompanied by increased morbidity and mortality and constitutes a substantial part of medical care. Antihypertensive intervention reduces the cardiovascular morbidity and mortality. The aims of the study were to evaluate the relationship between cardiovascular risk factors and the blood press...

journal_title：Blood pressure

authors： Larsen CT,Sørum C,Hansen JF,Jensen HA,Rasmussen V

更新日期：2000-01-01 00:00:00

abstract：:Candesartan is a new angiotensin II type 1 (AT 1 ) receptor blocker that produces more effective 24-h blood pressure lowering than losartan in hypertensive patients. In in vitro tissue preparations, candesartan displays insurmountable antagonism of the responses to angiotensin II. Both irbesartan and EXP-3174, the act...

journal_title：Blood pressure

authors： Morsing U Brandt-Eliasson L Renberg T Abrahamsson P

更新日期：2000-01-01 00:00:00

abstract：:Treatment with angiotensin-converting enzyme (ACE) inhibitors is frequently associated with persistent dry cough. This side effect is thought to be due to the non-specific action of ACE inhibitors, which, in addition to suppressing the renin-angiotensin system (RAS), leads to the accumulation of kinins, encephalins an...

journal_title：Blood pressure

authors： Tanser P,Campbell LM,Carranza J,Karrasch J,Toutouzas P,Watts R

更新日期：2000-01-01 00:00:00

abstract：:The second Swedish Trial in Old patients with Hypertension (STOP-Hypertension-2) was conducted to compare the effects of 'newer( antihypertensive therapies (angiotensin converting enzyme [ACE] inhibitors and calcium antagonists) and established therapies (beta-blockers and diuretics) on cardiovascular mortality and mo...

journal_title：Blood pressure

authors： Hansson L

更新日期：2000-01-01 00:00:00

abstract：:Using both in vitro and in vivo techniques, it has repeatedly been shown that endothelium-dependent vasodilation (EDV) is impaired in different forms of experimental hypertension (SHR, Dahl salt-sensitive rat, DOCA-salt rat and renovascular hypertension). EDV has also been found to be impaired in primary, as well as i...

journal_title：Blood pressure

authors： Lind L

更新日期：2000-01-01 00:00:00

abstract：OBJECTIVE:To determine the factors influencing general practitioners' prescribing for patients with moderate hypertension, and to investigate their ability to assess patients' absolute risk of cardiovascular disease. DESIGN:Decision-making was assessed by a postal questionnaire involving five standardised example pati...

journal_title：Blood pressure

authors： Hamilton-Craig CR,Tonkin AL,Jobling RG

更新日期：2000-01-01 00:00:00

abstract：:The HEART project was conducted in general practice to determine whether lifestyle strategies, aimed at increasing physical activity and dietary modification, can be substituted for drug therapy in patients who have been well controlled on antihypertensive medication. In addition to blood pressure (BP) and risk factor...

journal_title：Blood pressure

authors： Reid CM,Maher T,Jennings GL,Heart Project Steering Committee.

更新日期：2000-01-01 00:00:00

abstract：:The purpose of this study was to test the hypothesis of a causal relationship between high insulin levels and the development of benign prostatic hyperplasia (BPH) and to determine the clinical, anthropometric, metabolic and insulin profile in men with fast-growing BPH compared with men with slow-growing BPH. The pres...

journal_title：Blood pressure

authors： Hammarsten J,Högstedt B

更新日期：1999-01-01 00:00:00

abstract：:To investigate further the relationship between atherosclerotic vascular disease and blood pressure, and the phenomenon of white coat hypertension, we performed a cross-sectional study of patients referred for carotid Doppler scanning, to determine the relationship between ambulatory blood pressure monitoring (ABPM) a...

journal_title：Blood pressure

authors： Landray MJ,Sagar G,Murray S,Beevers M,Beevers DG,Lip GY

更新日期：1999-01-01 00:00:00

abstract：:NORDIL--the Nordic Diltiazem Study (NORDIL)--is a prospective, randomized, open blinded-endpoint (PROBE), multicenter, parallel-group morbidity/mortality outcome study in hypertensive patients designed to compare an intervention strategy based on the calcium antagonist diltiazem with a strategy based on conventional a...

journal_title：Blood pressure

authors： Hedner T

更新日期：1999-01-01 00:00:00

abstract：:A model of aortic ligation in mice with a hydronephrotic kidney (absence of macula densa) was used to determine the effects of aortic ligation on the renal renin-angiotensin system (RAS). Blood pressure increased from 83 +/- 2 to 133 +/- 8 mmHg within 7 days after aortic ligation (p < 0.01). Aortic ligation increased ...

journal_title：Blood pressure

authors： Zhang DY,Morgan TO

更新日期：1999-01-01 00:00:00

abstract：:We wanted to investigate whether time to steady state was reached within 2 h of insulin infusion during isoglycemic hyperinsulinemic clamp, comparing the glucose uptake index (M/IG) with Bergman's insulin sensitivity index (Sip). We performed a 2-h oral glucose tolerance test and a 3-h isoglycemic hyperinsulinemic cla...

journal_title：Blood pressure

authors： Olsen MH,Andersen UB,Wachtell K,Ibsen H,Dige-Petersen H

更新日期：1999-01-01 00:00:00

abstract：:To explore whether a condition of severe heart failure results in alteration of the 24-h-blood pressure (BP) profile and BP circadian rhythm, 19 patients with severe heart failure (NYHA class III-IV, 17M, 2F, mean age 57+/-8 years) were considered and compared to a control group of age- and sex-matched normal subjects...

journal_title：Blood pressure

authors： Moroni C,De Biase L,Pannarale G,Bondanini F,Affricano D,Campa PP,Cassone R

更新日期：1998-11-01 00:00:00

abstract：AIM:To describe the limitation of physical activity, the cause of limitation of physical activity and symptoms of dyspnea and chest pain before and 2 years after coronary artery bypass grafting (CABG) in relation to a history of hypertension. METHODS:All patients from western Sweden who underwent CABG between 1988 and...

journal_title：Blood pressure

authors： Herlitz J,Caidahl K,Albertsson P,Karlsson T,Hartford M,Haglid M,Lurje L,Karlson BW,Sjöland H

更新日期：1997-11-01 00:00:00

abstract：:Physical pain is a major trigger for changes in many homeostatic systems of the body physiology. Our aim was to study the relationship between blood pressure, metabolism and pain perception in subjects with chronic pain symptoms. This was undertaken in a population-based study in primary health care, including subject...

journal_title：Blood pressure

authors： Nilsson PM,Kandell-Collén A,Andersson HI

更新日期：1997-09-01 00:00:00

abstract：:This 1-year, dose-titration, General Practitioner (GP) study compared efficacy, tolerability and safety of oral temocapril (10-40 mg once daily) with atenolol (25-100 mg once daily) in mild to moderate adult hypertensives (diastolic blood pressure (DBP) 95-114 mmHg). A 12-week dose-titration period, randomized 3:1 tem...

journal_title：Blood pressure

authors： Sierakowski B,Püchler K,Witte PU,Renneisen K,Delius W

更新日期：1997-07-01 00:00:00

abstract：:One-thousand-four-hundred-and-fifty-three patients admitted to a teaching hospital, haemodynamically stable and not severely ill nor in significant pain, were interviewed within 48 h of admission and demographic data and a detailed drinking history were obtained. Supine blood pressures (BP) were recorded on the day fo...

journal_title：Blood pressure

authors： Howes JB,Ryan J,Fairbrother G,O'Neill K,Howes LG

更新日期：1997-03-01 00:00:00

abstract：OBJECTIVES:Essential hypertension and insulin resistance frequently coexist; cyclosporine A (CsA) is known to induce hypertension which has been used as a model for essential hypertension. The present study aimed to evaluate whether elevated blood pressure and insulin resistance coexist during CsA therapy to prove the ...

journal_title：Blood pressure

authors： Kutkuhn B,Hollenbeck M,Heering P,Koch M,Voiculescu A,Reinhard T,Grabensee B

更新日期：1997-01-01 00:00:00

abstract：:In order to study the contribution of the nitric oxide (NO)-pathway to cholinergic vasodilatation in the resistance vessels of the human forearm, we infused acetylcholine (ACh; 0.1 1000 ng/kg/min) or methacholine (MCh; 0.1 A 100 ng/kg/min) in the presence of saline, the NO-scavenger and guanylate cyclase inhibitor met...

journal_title：Blood pressure

authors： Bruning TA,Chang PC,Kemme MJ,Vermeij P,Pfaffendorf M,van Zwieten PA

更新日期：1996-11-01 00:00:00

abstract：:Low birth weight and high placental weight are associated with increased cardiovascular morbidity and mortality. Children born after hypertensive pregnancies have higher blood pressure than children born after normotensive pregnancies. Hypertension in pregnancy is considered a major risk factor for intrauterine growth...

journal_title：Blood pressure

authors： Himmelmann K,Himmelmann A,Niklasson A,Svensson A

更新日期：1996-09-01 00:00:00

abstract：:Losartan represent a novel approach in the treatment of hypertension. Clinical trials have reported a very low incidence of side effects. We describe two patients who developed increases in alanine/aspartate amino transferase of 8 and 15 times the upper normal limit, as well as thoracic pain, after a short time of tre...

journal_title：Blood pressure

authors： Nygaard B,Strandgaard S

更新日期：1996-05-01 00:00:00

abstract：:Serotonin stimulates phospholipase A(2)(PLA(2)) leading to the production of prostaglandin products, several of which are vasoconstrictors. We hypothesised that the elevated vascular responsiveness to serotonin in deoxycorticosterone acetate (DOCA)-hypertensive rats is due in part to augmented production of vasoconstr...

journal_title：Blood pressure

authors： Kanagy NL,Mecca TE,Webb RC

更新日期：1996-03-01 00:00:00

abstract：:Patients with severe hypertension with retinoscopic bilateral papilloedema only are not classically regarded as having malignant hypertension (MHT). We have encountered 23 such patients between 1965-1993, whilst over a similar period we have seen 315 patients who fulfilled the conventional criteria for MHT with bilate...

journal_title：Blood pressure

authors： Lip GY,Beevers M,Dodson PM,Beevers DG

更新日期：1995-11-01 00:00:00

abstract：:The aim of the present study was to compare insulin sensitivity and catecholamine responses to insulin in lean, hypertensive (HT) and normotensive (NT) premenopausal women. HT (BP 149 5/99 +/- 2 mmHg, n = 14) and NT (BP 128 +/- 4/81 +/- 2 mmHg, n = 12) were matched for age (46 +/- 1 vs. 47 +/- 1 years) and body mass i...

journal_title：Blood pressure

authors： Nordby G,Moan A,Kjeldsen SE,Eide IK,Os I

更新日期：1995-09-01 00:00:00

abstract：:To investigate the factors responsible for the morning rise in blood pressure (BP) in obstructive sleep apnea syndrome (OSAS) we examined a group of 253 consecutive snorers or OSAS patients. On the basis of their AHI the patients were classified in four groups. BP was measured on the evening before sleep onset and on ...

journal_title：Blood pressure

authors： Sforza E,Lugaresi E

更新日期：1995-07-01 00:00:00

abstract：:Since there appear to be important interactions between mechanisms of salt-sensitive and carbohydrate-sensitive hypertension, the goal of this study was to evaluate the effects of greatly reducing dietary salt intake and removal of one kidney (to increase salt sensitivity) on the hemodynamic and metabolic responses to...

journal_title：Blood pressure

authors： Donnelly R,Ho H,Reaven GM

更新日期：1995-05-01 00:00:00

abstract：:Elevated intracellular free calcium (Ca2+) has been proposed as a mechanism of alcohol-induced hypertension from animal experimental studies, but this has not been confirmed in man. In the present study, intraplatelet Ca2+ concentration (plt.[Ca2+]i) was measured in 83 middle-aged men, and the associations between alc...

journal_title：Blood pressure

authors： Ikai E,Ishizaki M,Tsuritani I,Ishida M,Noborisaka Y,Yamada Y

更新日期：1995-03-01 00:00:00

abstract：:Plasma level of adrenaline has been reported to be elevated in borderline hypertension. However, its role in developing and maintaining hypertension is still not completely understood. This study aimed to estimate the role of plasma adrenaline in developing hypertension. Ten patients with borderline hypertension (BHT)...

journal_title：Blood pressure

authors： Minatoguchi S,Ito H,Ishimura K,Suzuki T,Tonai N,Mori M,Hirakawa S,Fujiwara H

更新日期：1995-03-01 00:00:00

abstract：:Medullipin I (Med I) is a vasodepressor prohormone which is continuously elaborated into the renal venous effluent (RVE) of isolated rat kidneys perfused under high pressure. We have improved the yield of Med I by substituting saline for the albumin perfusate previously reported; and considerably improved refinement b...

journal_title：Blood pressure

authors： Brooks B,Byers LW,Muirhead EE,Muirhead M,Pitcock JA,Maddipati KR,Maxey KM

更新日期：1994-11-01 00:00:00

abstract：:Atherosclerosis is characterized by hypertrophy of the vascular media, intimal thickening and lipid-containing plaques. Atherosclerosis is a progressive systemic vascular disease which leads to impaired tissue perfusion due to vascular obstruction. In advanced stages it is often complicated by thrombosis. Recent resea...

journal_title：Blood pressure

authors： Wennmalm A

更新日期：1994-09-01 00:00:00

abstract：:The BBB study (Swedish for Behandla Blodtryck Bättre or Treat Blood Pressure Better) was a multicenter trial designed to investigate three aspects of antihypertensive treatment: i) Is it possible to lower the diastolic blood pressure further in "well-treated" hypertensive patients through intensified therapy? ii) Can ...

journal_title：Blood pressure

authors： Hannson L

更新日期：1994-07-01 00:00:00

abstract：:Plasma atrial natriuretic peptide (ANP), plasma and 24-h urine catecholamines, plasma renin activity (PRA), and serum aldosterone were studied in offspring of hypertensive and normotensive families [n = 82; age 37 +/- 7 years (mean +/- SD)]. Despite higher age, higher blood pressure, and higher urine excretion of cate...

journal_title：Blood pressure

authors： Mo R,Myking OL,Lund-Johansen P,Omvik P

更新日期：1994-07-01 00:00:00

abstract：:In order to study the role of opioid receptors in two models of experimental hypertension the binding of 3H-naloxone to membranes prepared from discrete brain regions and spinal cord was determined. Renal hypertensive rats (RHR) were found to have a greater density of 3H-naloxone binding sites in the hippocampus and h...

journal_title：Blood pressure

authors： Widy-Tyszkiewicz E,Kotapski J,Czlonkowski A

更新日期：1994-05-01 00:00:00